Statistically significant enhanced CD62P exposure was observed only for the broadly reactive WIM8E5 and HLA-A2/A28-specific SN607D8, whereas GV5D1 (anti-HLA A1/A23/A24) showed a trend of enhanced CD62P exposure, but this was not statistically significant.
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A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation.
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