Beyond Dopamine: GABA, Glutamate, and the Axial Symptoms of Parkinson Disease.

Front Neurol · 2018 · PMC6168661 · PMID 30319535

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0.0670

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showed a trendp = 0.067so close (0.05 < p ≤ 0.1)

For the summary score incorporating all the axial symptoms from the UPDRS, basal ganglia GABA levels showed a trend-level association in the full patient group (Spearman's rho = 0.441, p = 0.067), which was significant in the subgroup of akinetic rigid patients (Spearman's rho = 0.671, p = 0.034), but not in the subgroup of tremor-dominant patients (Spearman's rho = 0.345, p = 0.403).

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