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Long term effects of once-only flexible sigmoidoscopy screening after 17 years of follow-up: the UK Flexible Sigmoidoscopy Screening randomised controlled trial.

Lancet · 2017 · PMC6168937 · PMID 28236467

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Distal colorectal cancer mortality was reduced by 66% (HR 0·34 [95% CI 0·26–0·46]), and proximal colon cancer mortality was reduced by 12%, although it did not reach statistical significance (0·88 [0·70–1·10]; table 3 ).

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