The activated Treg (FrII) fraction exhibited an increasing trend after anti‐PD‐1 treatment (Figure 3 E).
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Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody.
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Patients with high PD‐1 in effector memory and effector subsets, such as CD4+ Tem and Te, tended to have shorter survival, but this did not reach statistical significance.