Although CD8 + T cell proliferation was not significantly inhibited by naringenin with the concentrations used, IFN-γ production from CD8 + T cells appeared to be dose-dependently inhibited and this effect was clearly significant at high level of naringenin (80 μM).
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Naringenin Modifies the Development of Lineage-Specific Effector CD4<sup>+</sup> T Cells.
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