Barely Significant
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clearly significant

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clearly significantp = 1.14E-080.0× alphaqualified
This raises the question whether the observed alteration in mib1 ta52b mutant neural tube proportions may be a secondary consequence of this reduction in cell number? Our observations argue against this hypothesis: First, the injection of NICD promotes a partial but clearly significant (p = 1.14E-08) restoration of neural tube proportions (Fig. 8p,q ) while triggering only a minor and non-significant (p = 0.129) increase in neural tube cell number (Supplementary Fig.
clearly significantp < 0.0010.0× alphaqualified
Nevertheless, the effect was clearly significant and similar in magnitude, to that it was found in the model without controlling, considering the subset of patients ≥70 years old (absolute increase = 2.8%; p < 0.001) and of the male gender (absolute increase = 2%, p = 0.03).
clearly significantP < 0.0010.0× alphaqualified
Confirming the MS data, T cells had intracellular levels of C3, and confirming the translocation observed in the MS data, the quantitative data from the images of C3 staining showed slightly higher C3 abundance in the nucleus compared to the cytosol upon TCR stimulation which was clearly significant ( P < 0.001) ( Figure 2D ).
clearly significantP < 0.0010.0× alphaqualified
Reversing the causal ordering (hs-CRP → index → CircS) changed the picture: both the CHG index and METS-IR produced clearly significant indirect effects (both ACME P < 0.001), pointing toward a model in which systemic inflammation feeds into CircS risk partly by perturbing atherogenic lipid handling and insulin homeostasis.
clearly significantP <0.0010.0× alphaqualified
To handle possible regression toward the mean biases, we also checked these changes with ANCOVA using the baseline value as a covariate; the cluster differences remained clearly significant ( P <0.001) for the changes related to both time points for NRS-7d, pain severity, pain interference, and life control.