Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial.

9 , 17 The reduction in the proportion of time spent in hypoglycaemia below 3·9 mmol/L with closed-loop therapy was statistically significant; time below 3·5 mmol/L and 2·8 mmol/L did not reach statistical significance.

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