Meanwhile, the proportion of both PD-1 + CD4 + T cells (12.49±1.82 vs 9.97±1.55) and PD-1 + CD8 + T cells (4.01±0.51 vs 2.29±0.44) was greater in COPD patients than non-COPD subjects, although the difference in CD4 + T cell percentage did not reach statistical significance ( P =0.40; Figure 5C and D ).
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Glucagon-like peptide-1 receptor (GLP-1R) signaling ameliorates dysfunctional immunity in COPD patients.
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