GSTM1 null genotype and drug-related AE The number of drug-related AEs and the number of subjects with drug-related AEs were higher in the GSTM1 null subjects than the GSTM1 functional subjects, although it failed to reach statistical significance ( Table 2 ).
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Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity.
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