Strategies to Preserve Cognition in Patients With Brain Metastases: A Review.

Front Oncol · 2018 · PMC6189295 · PMID 30356657

Europe PMC DOI

hedged sentence

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

did not reach statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

Memantine was well tolerated and although the trend toward delayed recall (the primary endpoint) did not reach statistical significance ( p = 0.059), memantine did delay time to cognitive decline and reduced the rate of decline in memory, executive function, and processing speed ( 1 ).

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