Diabetes mellitus (DM), pancreatic cancer, and liver metastasis were most frequently observed in patients with grade III and IV hepatotoxicity; while DM was a significant factor (AOR 2.3, 95% CI 1.0–5.1), the latter two were of marginal significance.
← all excerpts
Risk factors for erlotinib-induced hepatotoxicity: a retrospective follow-up study.
2
—
—
The sentences
Subgroup analysis using pancreatic cancer patients yielded marginally significant results with CYP3A4 inducers and erlotinib-induced hepatotoxicity.