SHANK3 Downregulation in the Ventral Tegmental Area Accelerates the Extinction of Contextual Associations Induced by Juvenile Non-familiar Conspecific Interaction.

Interestingly, we found that, although VTA-shShank3 mice discriminated between non-familiar conspecific-paired and non-social compartment at the post-TEST, they showed only a statistical trend towards an increase in their preference for the non-familiar conspecific-paired compartment before and after conditioning.

also in 2,798 other papers

When VTA-shShank3 mice were conditioned, they showed a trend towards a higher preference index between pre- and post-TEST (Figures 5K–M ), and a significant preference for the non-familiar conspecific-associated chamber vs. the non-social chamber at the post-TEST (Figure 5N ).

also in 53,322 other papers