Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia.

Acta Neuropathol Commun · 2018 · PMC6194687 · PMID 30340518

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hedged sentences

0.0010

closest p · 0.0× alpha

0.0600

boldest claim

The sentences

highly significantp < 0.001actually significant

Analysis of 12-month-old 5XFAD mice revealed a highly significant elevation of GPNMB protein levels when compared to age-matched WT or APP23 mice ( p < 0.001).

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did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

Quantification using a GPNMB-specific sandwich ELISA revealed that TBS-soluble GPNMB protein levels tended to be increased in AD patients in comparison to non-demented control individuals, but the difference did not reach statistical significance ( p = 0.06; Fig. 6g ).

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