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Studies on the metabolism and degradation of vancomycin in simulated in vitro and aquatic environment by UHPLC-Triple-TOF-MS/MS.

Sci Rep · 2018 · PMC6195508 · PMID 30341315

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showed a trendno p-value reported
M4 showed a trend to increase in the first two days in the PBS system and then decreased slightly from day 3.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.