Barely Significant
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Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia.

Mol Metab · 2018 · PMC6197675 · PMID 30170980

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Fourteen days after Gcgr deletion there was a trend towards up-regulation of Fgf21 expression that did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.