16 The retrospective analysis of the ICON3 trial for early-stage ovarian cancer showed a trend toward improved PFS in favor of the combination of carboplatin/paclitaxel instead of carboplatin alone, but no difference in OS. 22 The GOG 157 study compared 3 vs 6 cycles of carboplatin/paclitaxel and no difference was shown in RFS or OS between the regimens, although increased toxicity occurred with 6 cycles. 23 In our study, we have accurate data on chemotherapy available for each individual case, based on an interdisciplinary tumor board decision in accordance with the international guidelines.
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Impact of the new FIGO 2013 classification on prognosis of stage I epithelial ovarian cancers.
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