Association Between Statin Use and Cardiovascular Events After Carotid Artery Revascularization.

In contrast, a recent retrospective registry‐based analysis of 397 patients undergoing carotid stenting showed a trend toward lower risk of 30‐day events among patients treated with high‐dose statins, suggesting a potential dose‐dependent benefit of statins in this population. 35 Furthermore, clinical trials of patients with stable coronary artery disease, such as TNT (Treating to New Targets), suggest an incremental clinical benefit of high‐dose statin therapy over moderate‐dose therapy. 36 Although it is unclear why we did not observe a similar dose response in the carotid stenosis population in this study, variations in study cohort and LDL levels may help explain this discrepancy.

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