A clearer association between cognitive benefit and IgG AUC was seen for COWAT (Spearman r = 0.673, p = 0.039); the association for ADAS-Cog11 likewise was stronger, but did not reach statistical significance (Spearman r = − 0.576, p = 0.088) (Fig. 6b , d ).
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FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac1, an active immunotherapy against tau protein pathology in Alzheimer's disease.
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