A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects.

Even though the differences did not reach statistical significance, the results are in agreement with lowest anisotropy values of collagen fiber orientation found for scaffold R (Supplementary Fig. 3d ).

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However, highly significant differences were found in the primary orientation Φ M of the mineralized trabecular network for scaffold A in comparison with scaffold B and empty control (Fig. 8b ).

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