Multi-omic based molecular profiling of advanced cancer identifies treatable targets and improves survival in individual patients.

While there was a trend towards improved overall survival with targeted therapy compared with non-targeted therapy, this did not reach statistical significance ( P =0.23) (Figure 6 ).

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Taking all follow-up cases into account, a significant superiority of our approach could not be proven but a positive trend was observed, which is already a remarkable outcome, in particular for individual patients (Figure 3a and Figure 6 ).

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