Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators.

For all three regions where both trait and variant have appropriate equivalents in three previous GWASs ( Aguirre-Gamboa et al., 2016 , Orrù et al., 2013 , Roederer et al., 2015 ), our findings replicated with nominal significance (p < 0.05) or showed a trend in the same direction in publicly available data ( Table S2 ).

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