Application of Weighted Gene Co-Expression Network Analysis to Explore the Key Genes in Alzheimer's Disease.

J Alzheimers Dis · 2018 · PMC6218130 · PMID 30124448

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The results showed that in aged 14–month-old APP/PS-1 transgenic mice, expression levels of MT1, MT2, ADD3, RAB31 , and MSX1 were increased; upregulation of NOTCH2 was observed in 6-month-old transgenic mice; VCAN and EHD1 showed a trend of increase in expression in14–month-old AD mice ( Fig. 6 ).

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