Triple therapy in the management of chronic obstructive pulmonary disease: systematic review and meta-analysis.

BMJ · 2018 · PMC6218838 · PMID 30401700

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a significant trendno p-value reported

Safety results showed a higher incidence of pneumonia in the triple therapy group than in the group receiving dual therapy of LAMA and LABA, with a significant trend to increase pneumonia incidence when compared with LAMA monotherapy (which did not increase incidence significantly).

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