Barely Significant
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Physical and mechanical therapies for lower limb symptoms in children with Hypermobility Spectrum Disorder and Hypermobile Ehlers-Danlos Syndrome: a systematic review.

J Foot Ankle Res · 2018 · PMC6222981 · PMID 30455744

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(2013) comparison of exercising to the hypermobile versus neutral knee range, the size of the mean difference in pain scores between groups points to possible clinical significance favouring exercising to the neutral knee range but this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.