We identified that a high KRT8/18 ratio signature is associated with early recurrence in HCC patients in two independent cohorts: the HBV-related HCC cohort showed a strong tendency towards significance ( KRT8/18 high: n = 28 , KRT8/18 low: 193 , P = .16) [35] .
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High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype.
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