Continuous performance test impairment in a 22q11.2 microdeletion mouse model: improvement by amphetamine.

When a single, non-target stimulus was introduced, the Df(h22q11)/+ mouse exhibited a near-significant decrease in discrimination sensitivity (d’) (Fig. 2a ; F 1,26 = 4.203, p = 0.051), a significantly decreased hit rate (Fig. 2b ; F 1,26 = 9.552, p = 0.005) and an increased response criterion (c) (Fig. 2a ; F 1,26 = 6.971, p = 0.014) relative to wild-type littermate controls.

also in 2,306 other papers