The exploratory analyses within the double-wild-type population suggest longer PFS in bevacizumab maintenance is associated with higher AREG levels whereas in the watch- and wait-arm higher AREG levels showed a trend toward shorter PFS (Figure 4 ).
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Amphiregulin (AREG) and Epiregulin (EREG) Gene Expression as Predictor for Overall Survival (OS) in Oxaliplatin/Fluoropyrimidine Plus Bevacizumab Treated mCRC Patients-Analysis of the Phase III AIO KRK-0207 Trial.
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