Cardioprotective cytokine interleukin-33 is up-regulated by statins in human cardiac tissue.

J Cell Mol Med · 2018 · PMC6237563 · PMID 30216659

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Fluvastatin also showed a trend towards down‐regulation of mRNA specific for sST2 in HACM in five donors tested (to 85% ± 24% after 24 h and to 62% ± 38% after 48 h as compared to the respective controls), but had no influence on the levels of ST2L mRNA (data not shown). 3.2 Statin‐induced IL‐33 expression is inhibited by the com

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