Looking more closely at those primary studies it became clear that one was misclassified ( Melartin et al., 2004 , OR(95%CI) = 2.14(1.06–4.31), the second was a cohort in which only five participants had residual symptoms so the effect could not be adequately assessed ( Ilardi, Craighead, & Evans, 1997 ), and the third showed a trend towards an effect but had a very small sample in which just 19 had residual symptoms ( Kennedy & Paykel, 2004 , n = 59).
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Risk factors for relapse and recurrence of depression in adults and how they operate: A four-phase systematic review and meta-synthesis.
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