Association of serum angiopoietin-2 with malnutrition, inflammation, atherosclerosis and valvular calcification syndrome and outcome in peritoneal dialysis patients: a prospective cohort study.

By univariate Cox analysis, serum Angpt-2 showed a highly significant association with all-cause mortality ( p = 0.007) as well as fatal and non-fatal cardiovascular events ( p = 0.001, Table 3 ).

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Across the three tertiles of serum Angpt-2, a significant trend effect was observed for body mass index, normalized protein catabolic rate, calcium × phosphorus product, hs-CRP, brain natriuretic peptide, lower-density lipoprotein cholesterol, left ventricular ejection fraction, total weekly urea clearance and residual renal function (all p < 0.05).

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