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Canakinumab in patients with systemic juvenile idiopathic arthritis and active systemic features: results from the 5-year long-term extension of the phase III pivotal trials.

Ann Rheum Dis · 2018 · PMC6241618 · PMID 30269054

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showed a trendno p-value reported
These data were further corroborated by the CR data, which showed a trend towards better improvement in the subgroup of patients who were naïve to biologics.

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