Active full-length DNA Aβ₄₂ immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology.

Aβ x-42 peptides were also reduced in brains from Aβ 42 peptide-immunized 3xTg-AD mice in the nonsoluble lysate and detergent-soluble lysates, but levels did not reach statistical significance ( p = 0.2766 for nonsoluble Aβ x-42 , p = 0.0815 for soluble Aβ x-42 ).

also in 111,027 other papers

Although the reductions in the detergent-soluble brain lysate fractions were obvious but statistically not significant, reductions in the nonsoluble brain lysates were highly significant.

also in 132,142 other papers