Interferon-α Combined With Herbal Compound "Songyou Yin" Effectively Inhibits the Increased Invasiveness and Metastasis by Insufficient Radiofrequency Ablation of Hepatocellular Carcinoma in an Animal Model.

11 In a randomized controlled trial, Lo et al reported that adjuvant interferon therapy showed a trend for survival benefit for postoperative hepatitis B-related HCC patients, especially in those with pTNM stage III/IVA tumors. 12 These findings were also consistent with the outcome of our previous randomized control trial, which showed that 18 months of postoperative IFN-α treatment delayed recurrence and prolonged patient survival. 13 Songyou Yin (SYY) is a traditional Chinese medicine (TCM) and contains 5 herbal compounds.

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