Identifying chondroprotective diet-derived bioactives and investigating their synergism.

Sci Rep · 2018 · PMC6249298 · PMID 30464238

Europe PMC DOI

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did not reach statistical significanceno p-value reported

IL1-induced MMP1 , MMP13 , ADAMTS4 and ADAMTS5 mRNA expression was consistently decreased by luteolin but did not reach statistical significance.

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a weak trendno p-value reported

Isoliquiritigenin and luteolin showed reactive oxygen species scavenging activity in chondrocytes whereas sulforaphane had no effect and apigenin showed only a weak trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.