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Differences in Intercellular Communication During Clinical Relapse and Gadolinium-Enhanced MRI in Patients With Relapsing Remitting Multiple Sclerosis: A Study of the Composition of Extracellular Vesicles in Cerebrospinal Fluid.

Front Cell Neurosci · 2018 · PMC6249419 · PMID 30498433

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Instead, we observed a statistically significant reduction in the number of CD19 + /CD200 + CSF-EVs in subjects with in the course of a clinical relapse ( p = 0.030) (Figure 3I ), whereas we observed differences in these two markers between subjects with rMS stratified according to the presence of gadolinium-enhanced lesions, but these differences did not reach statistical significance (Figures 4G – I ).

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