SASH1-deficient clones showed a highly significant increase in transmigrated and Matrigel (Sigma Aldrich, Steinheim, Germany)-invading cells ( Figure 2 A ).
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The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.
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The sentences
Thus, although a similar tumor burden was induced by the different cell lines, a drastic difference was apparent in tumor dissemination.