Serum alkaline phosphatase and the risk of coronary heart disease, stroke and all-cause mortality: Tehran Lipid and Glucose Study.

BMJ Open · 2018 · PMC6254490 · PMID 30478120

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

marginally significantp=0.058so close (0.05 < p ≤ 0.1)

Furthermore, each 1-SD increase in ALP level was associated with 11%, 20% and 10% higher risk of CHD, stroke and CVD events in the fully adjusted model, respectively, with the risk calculated for stroke being marginally significant (HRs (95% CI), 1.20 (0.97 to 1.49), p=0.058).

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did not reach statistical significanceno p-value reported

However, after further adjustment for TLGS risk factors (model 2), the aforementioned ALP tertiles were associated with 11% and 32% higher risks of events, values which did not reach statistical significance.

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