Re-expression of TRIM24 showed a trend in rescuing tumor growth but the change was not statistically significant.
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TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression.
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The sentences
We observed highly significant upregulation of TRIM28 mRNA in metastatic PCa as compared to benign and/or localized PCa in multiple microarray datasets 3 , 44 , 45 (Fig. 6a, b ).