Here, we found a highly significant overexpression of SPP1 in CRC tissue samples ( Figure 1 a).
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Circulating Levels of Osteopontin Predict Patients' Outcome after Resection of Colorectal Liver Metastases.
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Using this cut-off value, patients with high post-operative osteopontin levels showed a strong trend towards an impaired overall survival but statistical significance was not reached ( Figure 4 b).