Short-acting bronchodilators for the management of acute exacerbations of chronic obstructive pulmonary disease in the hospital setting: systematic review.

Syst Rev · 2018 · PMC6264607 · PMID 30497532

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did not reach statistical significanceno p-value reported

There was a greater change in dyspnoea measured by Borg scale when MDI plus spacer albuterol was administered (− 1.08 ± 2.01) compared to nebulised albuterol (− 0.73 ± 1.75), but this did not reach statistical significance [ 43 ].

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