Low Salivary Amylase Gene (<i>AMY1</i>) Copy Number Is Associated with Obesity and Gut <i>Prevotella</i> Abundance in Mexican Children and Adults.

Nutrients · 2018 · PMC6266693 · PMID 30388780

Europe PMC DOI

hedged sentences

0.0960

closest p · 1.9× alpha

0.1040

boldest claim

The sentences

borderline significantP = 0.096so close (0.05 < p ≤ 0.1)

However, the presence of less than six AMY1 copies showed a borderline significant association with obesity (OR = 1.521; 95% CI = 0.928–2.495; P = 0.096), and individuals with a low number of AMY1 copies (≤4) had a significantly higher risk of obesity than those with a high number (≥10) of AMY1 copies (OR = 1.536; 95% CI = 1.019–2.313, P = 0.040) ( Table 2 ).

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did not reach statistical significanceP = 0.104not close (p > 0.1)

However, a positive and significant correlation between AMY1 copy number and Prevotella abundance was observed in adults (r = 0.377; P = 0.011), while a positive correlation that did not reach statistical significance was observed in children (r = 0.189; P = 0.104) ( Figure 2 A).

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