Are cytokines (IL-6, CRP and adiponectin) associated with bone mineral density in a young adult birth cohort?

BMC Musculoskelet Disord · 2018 · PMC6267914 · PMID 30501623

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

borderline significancep = 0.058so close (0.05 < p ≤ 0.1)

For females (Table 6 ), a borderline significance was found for adiponectin at 22 y and total body BMD (− 9.9 mg/cm 2 95% CI: -18.3; 0.6; p = 0.058) and for the third tertile of adiponectin and lumbar spine BMD (− 17.8 mg/cm 2 95% CI: -34.9; − 0.9; p = 0.033).

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did not reach statistical significanceno p-value reported

Discussion In general, our findings point to an inverse association mainly between CRP and adiponectin at 22 years and BMD at the same age, although most of the results did not reach statistical significance.

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