Parallel synthesis of peptide-like macrocycles containing imidazole-4,5-dicarboxylic acid.

Molecules · 2012 · PMC6268944 · PMID 22569415

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a clear trendno p-value reported

Importantly, we did not observe a clear trend relating stereochemistry or size of the side chain in preventing the formation of the macrocycle, so we reason it would be possible to expand this library in the future to include greater diversity in these areas.

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