Trisomy 12 chronic lymphocytic leukemia expresses a unique set of activated and targetable pathways.

Haematologica · 2018 · PMC6269288 · PMID 29976738

Europe PMC DOI

hedged sentence

0.0552

closest p · 1.1× alpha

0.0552

boldest claim

The sentences

approached significanceP =0.0552so close (0.05 < p ≤ 0.1)

The association between +12 and atypical immunophenotype (moderate to strong expression of at least two markers including CD22, CD79b, strong surface immunoglobulin, and FMC7) approached significance (χ 2 test, P =0.0552). 4 , 15 Trisomy 12 cases were more likely to demonstrate unmutated IGHV genes ( P =0.0004) and express CD38 ( P =0.044) than del(13q) cases, with statistical significance.

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