Barely Significant
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A simple hydrophilic palladium(II) complex as a highly efficient catalyst for room temperature aerobic Suzuki coupling reactions in aqueous media.

Molecules · 2014 · PMC6270763 · PMID 24853715

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quite significantno p-value reported
It is worthy of mention that although relatively less yields of coupling products with aryl chlorides have been obtained compared to aryl bromides as substrates, these results are still quite significant, as they represent successful examples of the Suzuki-Miyaura reaction of activated aryl chlorides at room temperature using environmentally-benign reaction media.

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