It is interesting to note that even though the crude extract did not show notable activity against Tbr , several of the spCCC subfractions displayed such activity at quite significant levels, e.g., subfraction E9 with an IC 50 value 0.13 μg/mL against Tbr and an SI of 38.
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Antiprotozoal activity of Buxus sempervirens and activity-guided isolation of O-tigloylcyclovirobuxeine-B as the main constituent active against Plasmodium falciparum.
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