Barely Significant
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Effect of extrusion cooking on bioactive compounds in encapsulated red cactus pear powder.

Molecules · 2015 · PMC6272353 · PMID 25993418

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showed a trendno p-value reported
The isobetanin concentration was significantly affected ( p < 0.05) by temperature and the interaction of barrel temperature and screw speed; however, it showed a trend opposite to that observed for betanin.

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