The 2β Splice Variation Alters the Structure and Function of the Stromal Interaction Molecule Coiled-Coil Domains.

The addition of 25 mM CaCl 2 to the STIM1-OASF and STIM1-2β-OASF proteins resulted in CD spectra which showed a trend toward less negative ellipticity at both the 208 and 222 nm minima; however, this apparent loss in α-helicity was diminutive and not statistically significant ( Figure S3A–D ).

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