Simulations of blood as a suspension predicts a depth dependent hematocrit in the circulation throughout the cerebral cortex.

PLoS Comput Biol · 2018 · PMC6277127 · PMID 30452440

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a clear trendno p-value reported

Detailed analysis of the spectrum of individual microcirculatory blood flow paths illuminated a clear trend; namely that deeply penetrating microvessels convey more red blood cells than paths running closer to the pial surface.

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an overall trendno p-value reported

However, there is an overall trend of higher hematocrit being carried to lower cortical levels (layer-V/VI paths).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.