Complex role of miR-130a-3p and miR-148a-3p balance on drug resistance and tumor biology in esophageal squamous cell carcinoma.

Sci Rep · 2018 · PMC6277408 · PMID 30510209

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

failed to reach statistical significancep = 0.058so close (0.05 < p ≤ 0.1)

Enhanced apoptosis levels were also observed for KYSE-410 (43%); however, data barely failed to reach statistical significance (p = 0.058). miR-130a-3p and miR-148a-3p regulate p53-dependent apoptosis-pathway Finally, we aimed to identify modes of action of both miRNAs that are consistent with the observed effects on chemotherapy response and tumor biology.

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